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randomised controlled trial (European Randomised Study of Screening for Prostate Cancer [ERSPC]). Current Controlled Trials ISRCTN49127736.
not concealed, at least in part.* In 3 countries, randomisation occurred before consent was obtained; in the other 4 countries, only consenting participants were randomised, but allocation concealment was unclear.
blinded (outcome adjudication committees).*
7 European countries.
162 243 men 55–69 years of age (mean age 61 y). Some countries also enrolled …
Abstract and commentary also appear in ACP Journal Club.
Source of funding: Europe Against Cancer; Fifth and Sixth Framework Program of the European Union; Beckman Coulter; local agencies and health authorities in participating countries.