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randomised controlled trial (Detection of Ischemia in Asymptomatic Diabetics [DIAD]). ClinicalTrials.gov NCT00769275.
blinded (outcome adjudication committee).*
14 centres in the USA and Canada.
1123 patients 50–75 years of age (mean age 61 y, 54% men) who had type 2 diabetes diagnosed at ⩾30 years of age, no symptomatic or previously recognised coronary artery disease (CAD), and no history of ketoacidosis.
screening with adenosine-stress radionuclide myocardial perfusion imaging …
Source of funding: National Institutes of Health; Bristol Myers-Squibb Medical Imaging; Astellas Pharma.