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Therapeutics
Manuka honey improved wound healing in patients with sloughy venous leg ulcers

http://dx.doi.org/10.1136/ebm.14.5.148

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    Study design

    Design:

    randomised controlled trial.

    Allocation:

    concealed.*

    Blinding:

    blinded (statistician).*

    Study question

    Setting:

    vascular centres, leg ulcer clinics, and acute and community care hospitals.

    Patients:

    108 patients >18 years of age (mean age 68 y) who had a venous leg ulcer (VLU) <100 cm2 with ⩾50% of the wound bed covered in slough. Exclusion criteria were malignant ulcer, wound infection, presence of a cavity wound, use of antibiotics or oral immunosuppressants, poorly controlled diabetes, pregnancy or lactation, and previous enrolment in the study.

    Intervention:

    Wounds were cleansed with warm tap water and then treated with 5 g/20 cm2 Manuka honey (n = 54), or 3 g/20 cm2 hydrogel therapy (n = 54), weekly for 4 weeks. Use of Allevyn hydrocellular foam as …

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    Footnotes

    • Source of funding: Research and Education Foundation in Sligo General Hospital; European Wound Management Association; Health Research Board of Ireland.