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Aetiology
Higher red blood cell distribution width was associated with increased risk of mortality in adults ⩾45 years of age

https://doi.org/10.1136/ebm.14.5.151

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    Study question

    Is a higher red blood cell distribution width (RDW) associated with increased risk of mortality in adults ⩾45 years of age?

    Study design

    Design:

    cohort study.

    Setting:

    USA.

    Participants:

    8175 participants ⩾45 years of age (mean age 62 y, 54% women) from the civilian non-institutionalised population. 3 participants were excluded because insufficient information was available to search the National Death Index.

    Risk factors:

    RDW values were divided by quintiles (12.6–12.95%, 13–13.4%, 13.45–14.05%, and >14.05%). Results were adjusted for age, sex, and ethnicity.

    Outcomes:

    all-cause mortality.

    Main results

    Overall, 2428 (30%) participants died during 12 years of follow-up. Increasing RDW …

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    Footnotes

    • Source of funding: Intramural Research program of the US National Institute on Aging and National Institutes of Health.