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The Intermountain Risk Score, based on common laboratory tests, was highly predictive of short-term mortality

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Study question

Can risk scores based on common laboratory tests predict short-term mortality?

Study design


prospective cohort study with ⩽5 years of follow-up.


Intermountain Healthcare in Utah, USA.


derivation (n = 71 921) and internal validation (n = 47 458) populations were patients ⩾18 years of age (mean age 55 y, 58% women) who had had a complete blood count (CBC) and basic metabolic profile (BMP) done. External validation cohorts were patients from the Third National Health and Nutrition Examination Survey (NHANES III, n = 16 372, mean age 48 y, 54% women) and patients having coronary angiography (mean age 61 y, 54% men).

Description of prediction guide:

the Intermountain Risk Score included, from the CBC, haematocrit, red cell distribution width, corpuscular volume, platelet count, platelet volume, corpuscular haemoglobin concentration, and total white blood cell count; from the BMP, serum concentrations of sodium, potassium, bicarbonate, creatinine, glucose, and calcium; and age. Each component was divided into quintiles, and a value ranging from 0 …

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  • Source of funding: no external funding.