Table of contents

Therapeutics

• Systematic review: Simple physical interventions such as hand washing and wearing masks can reduce spread of respiratory viruses (22 February, 2010)

  Benjamin J Cowling, Gabriel M Leung
• Systematic review: Combined educational and contraceptive interventions reduce unplanned teenage pregnancy, but how useful is this finding for policy and practice? (22 February, 2010)

  Adam Fletcher
• Randomised controlled trial: Feedback to internal medicine ward physicians from multidisciplinary antimicrobial use teams improves appropriate antimicrobial use (22 February, 2010)

  Forest W Arnold
• Systematic review: No difference between short-course and long-course antibiotics for bacterial meningitis in children, but available evidence limited (22 February, 2010)

  Diederik van de Beek, Matthijs C Brouwer
• PATRICIA randomised controlled trial: High efficacy of HPV 16/18 AS04-adjuvanted vaccine shown against CIN2+ associated with HPV-16/18 and non-vaccine oncogenic HPV types (22 February, 2010)

  Lisa Rambout
• Meta-analysis: Use of inhaled budesonide for 1 year does not increase risk of pneumonia in patients with chronic obstructive pulmonary disease (22 February, 2010)

  P John Rees
• Randomised controlled trial: “Hospital at home” care shows similar mortality and subsequent hospital admissions to hospital care for older patients with acutely decompensated chronic heart failure (22 February, 2010)

  Martin R Cowie
• Randomised controlled trial: Healthcare assistant case management may reduce depression symptoms in primary care patients with major depression more than usual care (22 February, 2010)

  Tony Kendrick
• Randomised controlled trial: Induction of labour improves maternal outcomes compared with expectant monitoring in women with gestational hypertension or mild pre-eclampsia (22 February, 2010)

  Baha M Sibai
• TOMBOLA randomised controlled trial: Immediate colposcopy referral in women with low-grade abnormal results on cervical cytology detects more CIN2 or worse lesions than cytological surveillance in primary care, but might lead to overtreatment (22 February, 2010)

  Marc Arbyn, Pierre Martin-Hirsch, Frank Buntinx
• Systematic review: Effects of physical fitness training on mortality, independence and disability after stroke unclear (22 February, 2010)

  Gudrun Boysen
• Randomised controlled trial: Antipyretic drugs do not reduce recurrences of febrile seizures in children with previous febrile seizure (22 February, 2010)

  Andrew L Lux
• Randomised controlled trial: Interactive booklet reduces antibiotic prescribing for respiratory tract infections in children, but not parent satisfaction (22 February, 2010)

  Alastair D Hay
• Randomised controlled trial: Web-based screening and brief motivational intervention reduces alcohol use in heavy-drinking undergraduates at up to 6 months (22 February, 2010)

  John T P Hustad, Brian Borsari
• Systematic review: Preventive antibiotics reduce infections but not mortality in adults with acute stroke (22 February, 2010)

  Stefan Schwarz
• Systematic review: Adding atypical antipsychotics to antidepressants increases response in treatment-resistant major depression but increases discontinuation as a result of adverse events (22 February, 2010)

  Gabor I Keitner
• Systematic review: Neuraminidase inhibitors produce a small reduction in duration of seasonal influenza in children and reduce transmission in affected households, but effects on serious complications unclear (22 February, 2010)

  Tom Jefferson
• Randomised controlled trial: Knee strengthening exercises at home, but not dietary intervention, reduce knee pain and improve knee function in overweight and obese people over 2 years (22 February, 2010)

  Stephen P Messier
• LEAP 2 randomised controlled trial: Primary care screening and brief counselling for overweight or mildly obese children does not improve BMI, nutrition or physical activity (22 February, 2010)

  Mark S Tremblay, Gary S Goldfield
• Systematic review: Corticosteroids added to antibiotic therapy aid pain resolution in adults with sore throat, particularly severe or exudative sore throat (22 February, 2010)

  Warren McIsaac
• Systematic review: Cochrane Review highlights the need for more targeted research on the tolerability of malaria chemoprophylaxis in travellers (22 February, 2010)

  Patricia Schlagenhauf
• ABOARD randomised controlled trial: No difference in peak troponin level in immediate versus delayed (next working day) intervention for acute coronary syndrome without ST-segment elevation (22 February, 2010)

  Christopher B. Granger