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Randomised controlled trial
Induction of labour improves maternal outcomes compared with expectant monitoring in women with gestational hypertension or mild pre-eclampsia
  1. Baha M Sibai
  1. Professor Baha M Sibai
    Department of Obstetrics and Gynecology, University of Cincinnati College of Medicine, 231 Bethesda Avenue, Cincinnati, OH 45267, USA; baha.sibai{at}

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Hypertension is the most common medical disorder during pregnancy, with the majority being due to gestational hypertension (GH) or pre-eclampsia.1 GH is defined as a systolic blood pressure (BP) of ≥140 mm Hg or a diastolic BP of ≥90 mm Hg on at least two occasions ≥4–6 h apart after 20 weeks of gestation in a woman known to be normotensive before pregnancy and before 20 weeks’ gestation.1 ,2 GH is considered severe if there is a sustained elevation in systolic BP to ≥160 mm Hg (United States and Canada)1,,4 or ≥170 mm Hg (Royal College of Obstetricians and Gynaecologists, UK, and Australia and New Zealand)5 ,6 or in diastolic BP to ≥110 mm Hg.1-6 Pre-eclampsia is defined as hypertension in association with proteinuria.1,,6 The reported rate of GH is between 6% and 17% in nulliparous women and between 2% and 4% in multiparous women.1 The rate of pre-eclampsia is between 2% and 7% in nulliparous women and 1% in multiparous women.1 In addition, most cases of GH and pre-eclampsia are mild, and the majority (approximately 90%) occur at ≥36 weeks’ gestation.1 ,2

Management of women with mild GH or …

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  • Competing interests BMS has served as a consultant for Beckman Coulter and Ortho-Clinical Diagnostics to advise on markers for pre-eclampsia