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Randomised controlled trial
Early therapeutic exercise in the first week after grade 1 or 2 ankle sprain improves subjective ankle function compared to standard RICE treatment
  1. Rogier M van Rijn
  1. Department of General Practice, Erasmus MC University Medical Center, Rotterdam, The Netherlands
  1. Correspondence to Rogier M van Rijn
    Department of General Practice, Erasmus MC University Medical Center, Room wk-109, PO Box 2040, 3000 CA Rotterdam, The Netherlands; r.vanrijn{at}

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Ankle sprains are one of the most common injuries of the human musculoskeletal system. Despite the number of sprains sustained and the total costs induced, ankle sprains are still considered as innocent lesions from which patients can recover without serious consequences. However, a recent systematic review showed that 1 year after an initial sprain a large proportion of patients suffer from residual symptoms.1 There are indications that treatment consisting of exercises may be an effective approach.2 Hence, the purpose of the present study was to compare an accelerated protocol for functional rehabilitation with the current best treatment for improving recovery from ankle sprain.


Ten patients (aged 16–65 years) with an acute grade 1 or grade 2 ankle sprain attending an emergency department or sports injury clinic were included. Patients were excluded if they had a complete rupture of the …

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  • Competing interests None.