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Randomised controlled trial
Odds of favourable 3-month outcome following ischaemic stroke are greatest when treatment with intravenous alteplase is initiated up to 90 min following event, with no benefit seen if alteplase is given after 270 min

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Footnotes

  • Competing interests RIL has been supported by Boehringer Ingelheim for attending national stroke and cardiovascular conferences. He is the Co-Principal Investigator of the Third International Stroke Trial (IST-3).