Article Text

Download PDFPDF
Randomised controlled trial
Morning-only polyethylene glycol preparation for afternoon colonoscopy is superior to traditional evening-before preparation
  1. Suryakanth R Gurudu
  1. Division of Gastroenterology, Mayo School of Medicine, Scottsdale, Arizona, USA
  1. Correspondence to Suryakanth R Gurudu
    Division of Gastroenterology, Mayo Clinic in Arizona, Mayo School of Medicine, 13400 East Shea Boulevard, Scottsdale, AZ 85259, USA; gurudu.suryakanth{at}

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Commentary on:


Colonoscopy is a valuable diagnostic and therapeutic tool in colon cancer screening and prevention. Earlier studies have reported higher failure rates and lower adenoma detection rates among patients undergoing colonoscopy in the afternoon,1 2 and poor bowel preparation is considered to be the main cause for these results.2 3 Inadequate bowel preparation can result in longer procedure time, missed lesions and reduced screening intervals, thereby increasing cost and complications. Though there are several factors implicated in successful completion of a colonoscopy, quality of bowel preparation and timing of colonoscopy are considered two modifiable factors4 5 to improve successful completion. Therefore investigators in this study performed a randomised endoscopist-blinded study to compare the efficacy of bowel cleansing with one gallon (4 litres) polyethylene glycol (PEG) in the morning of an afternoon colonoscopy, with that of traditional evening-before regimen.


This is a prospective randomised endoscopist-blinded study in which investigators compared the bowel cleansing …

View Full Text


  • Competing interests None.