Table of contents

Therapeutics

• Systematic review: Intensive insulin therapy in hospitalised patients increases the risk of hypoglycaemia and has no effect on mortality, infection risk or length of stay (11 June, 2011)

  Ebenezer Nyenwe
• Randomised controlled trial: Behavioural therapy is more effective than delayed treatment for persistent postprostatectomy incontinence (24 June, 2011)

  Christine Norton
• Randomised controlled trial: Six-month interventions – parent-centred dietary modification alone or in combination with child-centred physical activity may reduce child BMI at 2 years (6 July, 2011)

  Anthea Magarey
• Systematic review and meta-analysis: Epinephrine for acute bronchiolitis, but not steroids alone, reduces hospital admissions (24 June, 2011)

  Shawn Ralston
• Systematic review and meta-analysis: High-dose statin before percutaneous coronary intervention lowers risk of periprocedural myocardial infarction and 30-day major cardiac adverse events (6 August, 2011)

  Anthony A Bavry
• Randomised controlled trial: The combination of phentermine and topiramate is an effective adjunct to diet and lifestyle modification for weight loss and measures of comorbidity in overweight or obese adults with additional metabolic risk factors (21 September, 2011)

  Amanda G Powell, Caroline M Apovian, Louis J Aronne
• Randomised controlled trial: Calcium supplements may increase the risk of cardiovascular events in postmenopausal women (25 October, 2011)

  Barbara J Boucher
• Randomised controlled trial: Laparoscopic antireflux surgery and esomeprazole similarly efficacious for symptoms in people with gastro-oesophageal reflux disease who respond well to proton pump inhibitors (23 August, 2011)

  George Triadafilopoulos
• Randomised controlled trial: Continuous glucose monitoring in children and adults with well-controlled type 1 diabetes reduces hypoglycaemia (29 July, 2011)

  Breay Paty
• Systematic review and meta-analysis: Intraoperative complications are more common with laparoscopic than with open colorectal surgery (23 August, 2011)

  Tommie Mynster
• Systematic review and meta-analysis: No increased risk of caesarean or instrumental delivery for nulliparous women who have epidural analgesia early in (term) labour (26 September, 2011)

  Siranda Torvaldsen, Christine L Roberts
• Systematic review: The allergy protective effects of fish oil: A matter of timing? (28 November, 2011)

  Nina D'Vaz, Susan L Prescott
• Randomised controlled trial: Similar rates of relapse and time to return to normal activity with 2 or 5 days of systemic corticosteroids after asthma exacerbation but study confirmation of equivalence would require further study (28 November, 2011)

  Brian H Rowe