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Calcium supplementation is widely used for osteoporosis (OP) prevention and treatment. Many women buy calcium supplements, ±vitamin D. The authors' earlier randomised controlled trial (RCT) and meta-analysis suggests that calcium supplementation increases cardiovascular-event risks provoked controversy, as has this report.1,–,3
The ‘Women’s Health Initiative Calcium/vitamin D Supplementation Study' (WHICaD) limited access data set of 36 282 community-dwelling postmenopausal women comparing calcium plus vitamin D with placebo over 7 years was re-examined for effects of personal (preprotocol) calcium usage, adjusted for other cardiovascular disease (CVD) risk factors, followed by meta-analysis of the data on non-personal calcium users and from eight similar studies (some data previously unpublished; …
Competing interests None.
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