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Cohort study
Cohort analysis finds that the proportion of people who meet high risk criteria for colorectal, breast or prostate cancer screening based on family history increases between age 30 and 50
  1. Harvey J Murff
  1. Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA
  1. Correspondence to Harvey J Murff
    Department of Medicine, Vanderbilt University, 2525 West End Avenue, Suite 600, Nashville, TN 37203, USA; harvey.j.murff{at}

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Screening for breast, colorectal and prostate cancer is recommended to begin at an earlier age for individuals at increased risk because of their family history, compared with individuals at average risk. Some clinical guidelines have also suggested using more sensitive screening modalities for individuals with family histories of cancer, such as MRI for breast cancer screening. Since screening recommendations are different based on family history characteristics, it is important to know how family cancer history might change over time. Most family cancer history information is collected from patients on their initial visit and no evidence exists to help guide the clinician on how often family history information should be updated.


This study reviewed family cancer history information reported from individuals with either a personal or family history of …

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  • Competing interests None.