Table of contents

Therapeutics

• Systematic review and meta-analysis: High-quality evidence that spinal manipulative therapy for chronic low back pain has a small, short-term greater effect on pain and functional status compared with other interventions (25 October, 2011)

  Gert Bronfort
• Randomised controlled trial: Averaging clinic and home measures associated with reductions in within-patient variability and may give a better indication of blood pressure control (25 October, 2011)

  Kei Asayama, Lutgarde Thijs, Jan A Staessen
• Systematic review: Oxytocin for slow progress in the first stage of spontaneous labour is not associated with different rates of caesarean or assisted delivery compared with no treatment or delayed use in second stage (28 October, 2011)

  Michael Frölich
• Randomised controlled trial: In people with newly diagnosed type 2 diabetes an intensive dietary intervention, with or without an activity programme, improves glycaemic control over 12 months compared with usual care (28 October, 2011)

  Kirsten Coppell
• Randomised controlled trial: Early supplemental parenteral nutrition in critically ill adults increased infections, ICU length of stay and cost (25 October, 2011)

  Daren K Heyland
• Randomised controlled trial: Uterine artery embolisation associated with greater need for reintervention than surgical treatment for symptomatic uterine fibroids; quality of life similar though study underpowered (25 October, 2011)

  Martha Hickey, Jennifer L Marino, Fiona C Brownfoot
• Randomised controlled trial: Metformin is not significantly different from insulin for preventing fetal macrosomia in women with gestational diabetes (21 September, 2011)

  Steve L Hyer
• Systematic review and meta analysis: Inhaled corticosteroids for people with chronic obstructive pulmonary disease are associated with an increased risk of fracture (25 October, 2011)

  Nirupama Putcha, M Bradley Drummond
• Randomised controlled trial: In premenopausal women with recurrent UTI, antibiotics were more effective than capsules of cranberry extract for the prevention of UTI, but resistance was higher in the antibiotic group (20 October, 2011)

  Liza Genao
• Systematic review and meta-analysis: Review: excisional, and perhaps ablative treatments for precancerous cervical changes increase the risk for preterm birth (25 October, 2011)

  Joan Crane
• Randomised controlled trial: Tiotropium is superior to salmeterol in reducing frequency of exacerbations: but the effect of adding tiotropium to the combination of inhaled corticosteroid and long-acting β(2)-agonist remains unclear (22 November, 2011)

  Rick Hodder
• Randomised controlled trial: Antiretroviral combination therapy markedly reduces risk of heterosexual HIV-1 transmission (22 November, 2011)

  Mathias Lichterfeld, Eric S Rosenberg
• Randomised controlled trial: Varenicline for 4 weeks prior to target quit date reduces prequit date smoking and increases 12-week abstinence (7 December, 2011)

  Gina Daubney Garrison
• Systematic review and meta analysis: Intensive glucose-lowering therapy in people with type 2 diabetes: what do we learn from a new meta-analysis of randomised controlled trials? (28 November, 2011)

  Fiona Turnbull, Sophia Zoungas