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Systematic review and meta-analysis
High-quality evidence that spinal manipulative therapy for chronic low back pain has a small, short-term greater effect on pain and functional status compared with other interventions
  1. Gert Bronfort
  1. Department of Research, Northwestern Health Sciences University, Bloomington, Minnesota, USA
  1. Correspondence to Gert Bronfort
    Department of Research, Northwestern Health Sciences University, 2501 west 84th street, Bloomington, Minnesota 55431, USA; gbronfort{at}

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Commentary on: OpenUrlCrossRefPubMedWeb of Science


Chronic low back pain continues to be a major socioeconomic problem in most parts of the world. Spinal manipulative therapy is one of the several conservative treatment options, which, based on results from numerous randomised clinical trials, has been included as one of the recommended therapies in several national clinical guidelines.


Rubinstein et al systematically evaluated evidence from randomised, placebo or active comparative clinical trials in which spinal manipulative therapy (spinal manipulation and/or spinal mobilisation) was used to treat chronic low back pain in adults. This represents an update from an earlier Cochrane review and the authors identified the latest trials by searching Cochrane CENTRAL, MEDLINE, EMBASE, CINAHL, PEDro and the Index to …

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