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Clinical recurrence (CR) of urinary tract infection (UTI) is common in premenopausal women. Practice guidelines recommend 6–12 months of prophylactic antibiotics for CR of UTI. A meta-analysis demonstrated that prophylaxis with antibiotics was 85% (RR 0.15, (0.08 to 0.28)) better than placebo in pre and postmenopausal women. However, antibiotics cause adverse effects (AEs) (RR 1.58 (0.47 to 5.28)) and antimicrobial resistance1 prompting great interest in safer prophylaxis options. In a meta-analysis of two randomised control trials, cranberries were 39% (RR 0.61, (0.40 to 0.91)) better than placebo in preventing CR of UTI in premenopausal women without causing severe AEs.2 In postmenopausal women, antibiotics were similar to cranberries in reducing CR of UTI.3 Beerepoot et al aimed to demonstrate that …
Competing interests None.
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