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  • Lifestyle modifications and pharmacotherapy for cardiovascular risk factors are associated with improvements in erectile dysfunction

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Therapeutics
Systematic review with meta-analysis
Lifestyle modifications and pharmacotherapy for cardiovascular risk factors are associated with improvements in erectile dysfunction
  1. Kew-Kim Chew
  1. Department of Men's Health, Keogh Institute for Medical Research, Perth, Australia
  1. Correspondence to Kew-Kim Chew
    Department of Men's Health, Keogh Institute for Medical Research, A Block, Queen Elizabeth II Medical Centre, Perth, WA 6009, Australia; kewkimchew{at}hotmail.com

https://doi.org/10.1136/ebmed-2012-100555

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    Commentary on: Gupta BP, Murad MH, Clifton MM, et al. The effect of lifestyle modification and cardiovascular risk factor reduction on erectile dysfunction: a systematic review and meta-analysis. Arch Intern Med 2011;171:1797–803.OpenUrlCrossRefPubMedWeb of Science

    Context

    Pharmacotherapies directly targeted towards the pathophysiology of erectile dysfunction (ED) are efficacious. But whether lifestyle modification and other pharmacotherapies that target one of the main underlying risks for ED, cardiovascular (CV) risk factors and disease can improve ED remains unclear.

    Methods

    An online search of peer-reviewed databases was conducted for randomised controlled clinical trials of lifestyle modification or pharmacotherapy of CV risk factors with a minimum intervention period of 6 weeks. Study selection was undertaken with a hierarchical approach by two of the authors acting independently.

    Erectile function was assessed with the 5-item International Index of Erectile …

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    Footnotes

    • Competing interests None.