Context

Acute rhinosinusitis (ARS) is a common reason for patients to visit a general practitioner (GP).1 ,2 In general practice, diagnosing ARS is based on clinical signs and symptoms such as nasal congestion, reduction/loss of smell and facial pain/pressure. Although self-limiting in the majority of patients within 1–4 weeks, symptoms consistent with ARS can considerably impair daily functioning.3

Traditionally, ARS has been regarded as a bacterial infection of the paranasal sinuses. Therefore, numerous randomised controlled trials (RCTs) have been performed comparing antibiotic treatment with placebo for mild–moderate ARS. The present study provides …