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Diagnosis
Cohort study
High-sensitivity troponin useful for diagnosis and prognosis in patients with acute coronary syndrome
  1. Eugenio Stabile,
  2. Alessia Agresta
  1. Department of Cardiology, Centro Polidiagnostico Stabile, Salerno, Italy
  1. Correspondence to : Eugenio Stabile
    Department of Cardiology, Centro Polidiagnostico Stabile, via diaz 32, Salerno 84100, Italy; geko50{at}hotmail.com

http://dx.doi.org/10.1136/ebmed-2012-100792

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    Context

    High-sensitivity cardiac troponin (hs-cTnT) determination has improved cTnT evaluation in patients with acute coronary syndrome (ACS). The hs-cTnT ‘normal value’ is considered to be <99th percentile (0.014 ug/l). Hs-cTnT can diagnose an acute myocardial infarction (AMI) earlier than common cTnT determinations, even in patients with previous CAD.1 ,2 Some studies have shown higher specificity of hs-cTnT in AMI diagnosis, compared with common cTnT determinations.3 Hs-cTnT is also a better predictor of death and heart failure in patients with chest pain and ACS during follow-up.1 ,2 ,4

    Methods

    The APACE study, a multicentre prospective trial, enrolled a total of 1181 consecutive patients who were admitted to the emergency department because of chest …

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