Context

Prophylactic antiplatelet therapy with aspirin reduces the risk of non-fatal myocardial infarction (MI), non-fatal stroke and vascular death in patients with known cardiovascular disease (CVD) and is of net benefit. The absolute reduction in recurrent events significantly exceeds the increase in major bleeding.1 However, the role of aspirin in primary prevention of CVD is not clear. According to the Antithrombotic Trialists Collaboration meta-analysis and other recent studies, the role of aspirin in primary prevention of CVD is of uncertain net value.1 Similarly, the benefit of aspirin therapy for …