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Randomised controlled trial
Application of 4% chlorhexidine solution for cord cleansing after birth reduces neonatal mortality and omphalitis
  1. Sarah Saleem
  1. Department of Community Health Sciences, Aga Khan University, Pakistan
  1. Correspondence to Dr Sarah Saleem
    Department of Community Health Sciences, Aga Khan University, Stadium Road, PO Box 35,00, Karachi 74800, Karachi, Sindh, Pakistan; sarah.saleem{at}aku.edu

https://doi.org/10.1136/eb-2012-100752

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    Commentary on: Arifeen SE, Mullany LC, Shah R, et al. The effect of cord cleansing with chlorhexidine on neonatal mortality in rural Bangladesh: a community-based, cluster-randomised trial. Lancet 2012;379:1022–8.OpenUrlCrossRefPubMedWeb of Science

    Context

    Four per cent chlorhexidine solution is considered as an ideal antiseptic for cord cleansing after birth in newborns for the prevention of infection-related mortality and morbidity. Currently the debate is focused on identifying the best frequency of its applications and its inclusion in safe delivery kits for home deliveries in resource-poor situations.1 ,2

    Methods

    A community-based, parallel cluster-randomised trial was conducted in Sylhet, Bangladesh to test the efficacy of two regimens of single and multiple applications of 4% chlorhexidine for cord cleansing compared to dry cord care in reducing neonatal morbidity and mortality. About 133 …

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    Footnotes

    • Competing interests None.