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Randomised controlled trial
Weight loss and improved fitness slow down the decline in mobility in obese adults with type 2 diabetes
  1. Krupa Shah1,
  2. Dennis T Villareal2
  1. 1Department of Geriatrics and Aging, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
  2. 2Section of Geriatrics, New Mexico Veterans Affairs Health Care System and Division of Geriatrics, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA
  1. Correspondence to: Dr Dennis T Villareal
    Section of Geriatrics, New Mexico Veterans Affairs Health Care System and Division of Geriatrics, University of New Mexico School of Medicine, Albuquerque, NM 87108, USA; Dennis.Villareal{at}va.gov

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Context

The increasing prevalence of type 2 diabetes (T2D) and its complications challenge our healthcare delivery systems. Indeed, the healthcare industry is vulnerable to the rising costs and faces challenges with respect to increased life expectancy and prevalence of chronic diseases. Adults with T2D often have limitations in mobility and experience increased risk of physical disability.1 Furthermore, the number of obese older adults with T2D has substantially increased in the last 20 years.2 Obesity among older adults is problematic because it not only increases the risk of medical complications but also causes physical dysfunction.3 Functional limitations associated with obesity and T2D exacerbate the age-related decline …

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