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Prevention
Systematic review with meta-analysis
Cranberry-containing products are associated with a protective effect against urinary tract infections
  1. Ann E Stapleton
  1. Department of Medicine, University of Washington, Seattle, Washington, USA
  1. Correspondence to : Dr Ann E Stapleton
    Department of Medicine, University of Washington, 1959 NE Pacific, Box 356423, Seattle, WA 98195, USA; stapl{at}uw.edu
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http://dx.doi.org/10.1136/eb-2012-100984

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    Commentary on: Wang CH, Fang CC, Chen NC, et al. Cranberry-containing products for prevention of urinary tract infections in susceptible populations: a systematic review and meta-analysis of randomized controlled trials. Arch Intern Med 2012;172:988–96.OpenUrlCrossRefPubMedWeb of Science

    Context

    Urinary tract infection (UTI) is a common clinical problem that often recurs, leading to the institution of preventive measures for recurrent UTI (rUTI).1 ,2 Antimicrobial prophylaxis is highly effective, but risks adverse effects and induction of resistance.1 ,2 These considerations and widespread increases in antimicrobial resistance have intensified interest in alternative means of preventing UTIs, such as cranberry products. However, few well-designed clinical trials were available for analysis in the last Cochrane review of cranberry for the prevention …

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