Table of contents

Therapeutics

• Randomised controlled trial: Radical prostatectomy does not improve survival compared to observation for localised prostate cancer in a prospective randomised trial (20 October, 2012)

  Joshua G Griffin, Jeffrey M Holzbeierlein
• Randomised controlled trial: Double-balloon catheter results in higher rate of vaginal delivery within 24 h when compared with dinoprostone vaginal insert (2 November, 2012)

  Anthony C Sciscione, Kelly Ruhstaller
• Randomised controlled trial: Lactobacillus probiotics may prevent recurrent UTIs in postmenopausal women (2 November, 2012)

  Jeremy P Dwyer, Peter L Dwyer
• Systematic review with meta-analysis: Statin-induced lowering of LDL cholesterol associated with a reduced risk for cardiovascular events, not likely outweighed by the risk of diabetes, for people at low short-term risk of cardiovascular disease (2 November, 2012)

  Robert Sidney Rosenson
• Randomised controlled trial: Postpartum bleeding is reduced with sublingual powdered misoprostol when compared with oxytocin injection, but a new formulation of misoprostol is unlikely to revolutionise postpartum haemorrhage care (2 November, 2012)

  Beverly Winikoff, Jill Durocher
• Randomised controlled trial: Early surgery in infective endocarditis with large vegetations significantly reduced mortality compared with conventional treatment (2 November, 2012)

  Marie-Christine Herregods, Paul Herijgers
• Randomised controlled trial: Coronary CT angiography decreases the length of stay in emergency department versus standard therapy in patients presenting with acute chest pain, but results in increased downstream testing and radiation exposure (4 December, 2012)

  James K Min, Reza Arsanjani
• Randomised controlled trial: Randomised trial of exercise dose in children reduces diabetes risk (as measured by insulin resistance) in both 20-min and 40-min doses (4 December, 2012)

  Aaron L Carrel
• Systematic review: HIV consensus guideline recommends antiretroviral treatment regardless of CD4 count, new regimens and possible regimen change for chronic low level viraemia (15 November, 2012)

  R Chris Rathbun
• Randomised controlled trial: One iron pill a day keeps fatigue away? (17 November, 2012)

  Pierre-Alexandre Krayenbuehl, Henriette Heinrich
• Systematic review with meta-analysis: Home-like environments for labour and birth: benefits for women and babies (17 November, 2012)

  Caroline S E Homer