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Therapeutics
Randomised controlled trial
Lactobacillus probiotics may prevent recurrent UTIs in postmenopausal women
  1. Jeremy P Dwyer1,
  2. Peter L Dwyer2
  1. 1Department of Medicine, Royal Melbourne Hospital, Parkville, Victoria, Australia
  2. 2Mercy Hospital for Women and University of Melbourne, Melbourne, Victoria, Australia
  1. Correspondence to: Peter L Dwyer
    Mercy Hospital for Women and University of Melbourne, 13 Brunswick St, Fitzroy, Melbourne, VIC 3065, Australia; pdwyer{at}connexus.net.au

https://doi.org/10.1136/eb-2012-100961

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    Commentary on: Beerepoot MA, Ter Riet G, Nys S, et al. Lactobacilli vs antibiotics to prevent urinary tract infections: a randomized, double-blind, noninferiority trial in postmenopausal women. Arch Intern Med 2012;172:704–12.OpenUrlCrossRefPubMedWeb of Science

    Context

    Urinary tract infection (UTI) is common; over half of all adult women will have a UTI, with a third having recurrent UTI. Women at higher risk of developing recurrence are older, postmenopausal, and incontinent and have cystocoeles with high postvoid residual volumes.1 Preventative strategies using prophylactic antibiotics may result in adverse side effects, antibiotic resistance and Clostridium difficile colitis. Therefore, women are increasingly looking for safe and effective non-antimicrobial alternatives. A recent systematic review and meta-analysis of randomised studies of products containing cranberry showed a protective effect against UTI, particularly in women with recurrent UTIs, …

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    Footnotes

    • Competing interests None.