Article Text
Statistics from Altmetric.com
Commentary on: OpenUrlCrossRefPubMedWeb of Science
Context
Intrahepatic cholestasis of pregnancy (ICP) is a heritable disease of pregnancy resulting in elevation of serum bile acids, pruritus and increased risk of poor fetal outcomes. It always resolves after delivery, but pruritus can be a cause of severe distress for the mother, and the fetus is at increased risk of intrauterine demise. The prevalence of ICP varies greatly by ethnicity and geography: rates of over 25% have been reported in South American Indians, although in most areas the prevalence is less than 2%.1 ,2
Ursodeoxycholic acid (UDCA) is a naturally occurring hydrophilic bile acid used in a variety of cholestatic liver diseases. The exact mechanism of benefit is not completely …
Footnotes
-
Competing interests None.
Request Permissions
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.