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  • Prophylactic antibiotics for caesarean section administered preoperatively rather than post cord clamping significantly reduces the rate of endometritis

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Therapeutics
Systematic review and meta-analysis
Prophylactic antibiotics for caesarean section administered preoperatively rather than post cord clamping significantly reduces the rate of endometritis
  1. R F Lamont1,2,
  2. J S Joergensen2
  1. 1 Division of Surgery, University College London,Northwick Park Institute of Medical Research Campus, Harrow, Middx, London, HAI 3UJ, UK
  2. 2 Department of Obstetrics and Gynaecology, University of Southern Denmark, Odense University Hospital, Sdr Boulevard 29, 5000 Odense C, Denmark
  1. Correspondence to : Professor Ronald F Lamont University of Southern Denmark, Sdr Boulevard 29, Odense, 5000 Odense C, Denmark;rflamont{at}aol.com

http://dx.doi.org/10.1136/eb-2013-101429

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    Commentary on: Baaqeel H, Baaqeel R. Timing of administration of prophylactic antibiotics for caesarean section: a systematic review and meta-analysis. BJOG 2013;120:661–9.OpenUrlCrossRefPubMed

    Context

    Antibiotic prophylaxis for women undergoing caesarean section (CS) has been proven to be beneficial in decreasing post-CS infectious morbidity in women at high-risk (in labour after membrane rupture), as well as low-risk (non-labouring with intact membranes).1 Evidence-based guidelines recommend the use of prophylactic antibiotics before surgical incision. An exception is made for CS, where narrow-range antibiotics are administered after umbilical cord clamping because of putative neonatal benefit. The use of preincision, broad-spectrum antibiotics may result in a lower rate of maternal morbidity with no disadvantage to the neonate.2 This systematic review and meta-analysis examines the maternal and neonatal …

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    Footnotes

    • Competing interests None.