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Statins are commonly used medications for the reduction of low-density lipoprotein cholesterol resulting in markedly improved cardiovascular disease outcomes.1 Prior studies with regard to acute kidney injury (AKI) risk in statin users versus non-statin users show mixed results. Dormuth and colleagues address the question of whether high-potency statin therapy is associated with increased hospitalisation for AKI compared to low-potency statin therapy, thereby decreasing indication bias for statin use as a confounder.
The Canadian Network for Observational Drug Effect Studies (CNODES) are an observational retrospective database meta-analysis of 2 008 003 patients without chronic kidney disease …
Competing interests None.