Table of contents

Therapeutics

• Systematic review and meta-analysis: Blood pressure reduction in elderly patients with hypertension decreases risk of adverse cardiovascular outcomes (1 May, 2014)

  Sripal Bangalore, Bethany Doran
• Cohort study: Benzodiazepines and opioids need to be prescribed with caution in advanced COPD (1 May, 2014)

  Nicholas T Vozoris
• Meta-analysis of randomised controlled trials: Similar 5-year clinical outcomes in patients with stable coronary artery disease and myocardial ischaemia managed with an initial approach of medical therapy compared with medical therapy plus percutaneous coronary intervention (1 May, 2014)

  R Andrew Archbold
• Randomised controlled trial: Trial suggests yoga and exercise lead to modest improvements in menopause-related quality of life: longer term studies are needed (4 June, 2014)

  Nancy Fugate Woods
• Systematic review and meta-analysis: For patients with chronic asthma not controlled with inhaled corticosteroids alone, long-acting β-agonists are associated with fewer exacerbations than leukotriene receptor agonists (4 June, 2014)

  Gene Colice
• Systematic review and meta-analysis: Dexamethasone may be a viable alternative to prednisone/prednisolone for the treatment of acute asthma exacerbation in the paediatric emergency department (10 June, 2014)

  Annie L Andrews, Annie N Simpson
• Randomised controlled trial: Radical prostatectomy reduces prostate cancer-specific mortality among men with intermediate-grade disease, but provides minimal benefit for men with low-grade and high-grade disease (10 June, 2014)

  Peter Albertsen
• Randomised controlled trial: Salpingectomy for tubal ectopic pregnancy is appropriate in the presence of healthy-looking contralateral tube (11 June, 2014)

  Togas Tulandi
• Systematic review and meta-analysis: Isoflavones hold limited promise for the treatment of menopausal vasomotor symptoms (17 June, 2014)

  Katherine M Newton
• Randomised controlled trial: A viscous lidocaine mouthwash is no better than placebo for improving oral intake in children with painful mouth ulcers (17 June, 2014)

  Vianney Descroix, Amélie E Coudert
• Randomised controlled trial: Evidence suggests dabigatran is an effective and safe treatment for patients with VTE requiring early parenteral therapy (16 May, 2014)

  Serena Granziera, Alexander T Cohen
• Randomised controlled trial: Citalopram decreases agitation in the context of Alzheimer's disease, but at doses higher than those commonly prescribed and at the expense of side effects (13 May, 2014)

  Benjamin R Underwood, Chris Fox
• Systematic review and meta-analysis: Non-vitamin-K oral anticoagulants reduce mortality, stroke and intracranial haemorrhage when compared with warfarin in randomised trials of patients with non-valvular atrial fibrillation (27 June, 2014)

  Benjamin A Steinberg