Statistics from Altmetric.com
By 2050, an estimated 135 million people will suffer from dementia globally.1 Caring for those with Alzheimer's disease (AD)—by far the most common form of dementia—is expensive, costing an estimated £23 billion per annum in the UK. As the disease progresses, neuropsychiatric symptoms such as depression, agitation and behavioural disturbance appear. The incidence of these symptoms, which predict institutionalisation and caregiver distress, is high—perhaps affecting as many as 95% of Alzheimer's sufferers.2 ,3
Historically, antipsychotic drugs have been administered for the treatment of agitation and aggression in this context. While there is evidence for modest efficacy for some antipsychotics, …
Competing interests None.
Provenance and peer review Commissioned; internally peer reviewed.
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.