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Randomised controlled trial
Lifestyle interventions in obese and overweight pregnant women do not reduce the risk of large-for-gestational age babies
  1. Shakila Thangaratinam
  1. Queen Mary, University of London, London, UK
  1. Correspondence to : Professor Shakila Thangaratinam, Women's Health Research Unit, Centre for Primary Care and Public Health, Blizard Institute, Barts and The London School of Medicine and Dentistry, Yvonne Carter Building, 58 Turner Street, Whitechapel, London E1 2AB, UK; s.thangaratinam{at}

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Pregnant women who are overweight or obese and undergo excessive gestational weight gain are at risk of maternal and fetal complications.1 Diet-based and physical activity-based interventions may improve pregnancy outcomes. Any reduction in the risk of high infant birth weight may lower rates of new-born complications and childhood obesity.2


The LIMIT trial evaluated whether antenatal lifestyle interventions in overweight (body mass index (BMI) 25–29.9 kg/m2) and obese (BMI≥30 kg/m2) women improved fetal and maternal outcomes.

Eligible women were recruited at between 10 and 20 weeks’ gestation from three …

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  • Competing interests Chief Investigator of i-WIP project.