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Aspirin is recommended in current international guidelines for women at heightened risk for preeclampsia. Preeclampsia occurs in 2–8% of pregnancies and is a leading cause for both maternal and fetal morbidity and mortality. Effective prevention approaches therefore have the potential for significant health benefits. In 1996 the US Preventive Services Task Force produced a report on the identification, prevention and treatment of preeclampsia, stating:
There is insufficient evidence to recommend for or against routine aspirin prophylaxis in pregnancy for the prevention of either preeclampsia […] or intrauterine growth retardation […]. Clinicians may wish to inform patients at high risk of preeclampsia that aspirin prophylaxis has been shown to …