Article Text

Download PDFPDF
Cohort study
Stricter systolic blood pressure control is associated with higher all-cause mortality in patients with chronic kidney disease
  1. Nisha Bansal
  1. University of Washington, Seattle, Washington, USA
  1. Correspondence to : Dr Nisha Bansal, University of Washington, Kidney Research Institute, 325 9th Avenue, Seattle, WA 98114, USA; nbansal{at}

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Commentary on: OpenUrlCrossRefPubMedWeb of Science


Hypertension is a major cause of mortality. Previous studies have identified a J-shaped association between systolic blood pressure (SBP) and risk of mortality, raising concerns about the safe limits of blood pressure lowering in certain patient populations. Patients with chronic kidney disease (CKD) represent 13% of the US population and have high prevalence of cardiovascular morbidity and a high mortality rate. However, data on optimal blood pressure targets in this high-risk patient population is limited. The few published trials of blood pressure in patients with CKD have primarily focused on kidney end points.1 ,2 Prior observational studies of patients with CKD have suggested that …

View Full Text


  • Competing interests None.

  • Provenance and peer review Commissioned; internally peer reviewed.