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Randomised controlled trial
Invasive revascularisation in patients with moderate intermittent claudication provides a significant improvement in quality of life compared with conservative treatment
  1. Andrew K Kurklinsky
  1. Correspondence to : Dr Andrew K Kurklinsky, Division of Cardiovascular Medicine, Mayo Clinic, 4500 San Pablo Rd, Jacksonville, FL 32224, USA; kurklinsky.andrew{at}

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In cases of severe intermittent claudication (IC), successful revascularisation provides significant symptomatic improvement. In cases of mild IC, revascularisation has exceedingly high risks. The choice between invasive revascularisation and non-invasive treatments for moderate severity IC is often difficult. Treatment benefits may be relative in terms of the effects on quality of life (QoL).


This trial randomised consecutive patients with moderate IC into two equal groups to compare the effects of revascularisation and non-invasive treatment on health-related QoL assessed by the Medical Outcomes Study Short Form 36 (SF-36) and Vascular Quality of Life Questionnaire (VascuQoL). Self-reported maximum walking distance (MWD) and IC distance (ICD) on a …

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  • Competing interests None.

  • Provenance and peer review Commissioned; internally peer reviewed.