Context

Population-based screening for prostate cancer (PCa) is not yet recommended. Despite the fact that the European Randomised study of Screening for PCa has repeatedly reported on a significant PCa mortality reduction in favour of prostate-specific antigen (PSA)-based screening,1 ,2 the harm–benefit ratio is far from optimal. This study assessed the accuracy of digital rectal examination (DRE) in men referred for to a specialty clinic for PCa evaluation.