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Multivessel coronary artery disease (MVCAD) may be found in patients subjected to coronary angiography. It is treated with coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI). The expanded use of PCI, following development of drug-eluting stents (DES), necessitated comparison of its outcomes with CABG (gold standard therapy). The SYNTAX (SYNergy between PCI with TAXUS and Cardiac Surgery) trial favoured CABG with regard to occurrence of cardiac death, myocardial infarction (MI), repeat revascularisation, and major cardiac and cerebrovascular events.1 New-generation DES and new antiproliferative agents have better efficacy and safety than …
Competing interests FWM was one of the principal investigators for the SYNTAX trial.
Provenance and peer review Commissioned; internally peer reviewed.