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  • An IVC filter and anticoagulation for 3 months is unlikely to show a benefit over anticoagulation alone for high-risk patients with acute pulmonary embolism

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Therapeutics/Prevention
Randomised controlled trial
An IVC filter and anticoagulation for 3 months is unlikely to show a benefit over anticoagulation alone for high-risk patients with acute pulmonary embolism
  1. Eric K Hoffer
  1. Department of Radiology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, USA
  1. Correspondence to : Dr Eric K Hoffer, Dartmouth Hitchcock Medical Center, Department of Radiology, One Medical Center Drive, Lebanon, NH 03755, USA; hoffer{at}hitchcock.org

http://dx.doi.org/10.1136/ebmed-2015-110230

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    Commentary on: Mismetti P, Laporte S, Pellerin O, et al; PREPIC2 Study Group. Effect of a retrievable inferior vena cava filter plus anticoagulation vs anticoagulation alone on risk of recurrent pulmonary embolism: a randomized clinical trial. JAMA 2015;313:1627–35.OpenUrlCrossRefPubMed

    Context

    Placement of an inferior vena cava (IVC) filter to prevent pulmonary embolism (PE) is recommended by multidisciplinary consensus guidelines only when anticoagulation is contraindicated, has resulted in a complication or has failed.1 ,2 Oddly, the only prospective randomised long-term filter efficacy study that demonstrated a reduction in the recurrent PE rate at 8-year follow-up (6.3% vs 15.1%) did so in a setting where both filter …

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    Footnotes

    • Competing interests None declared.

    • Provenance and peer review Commissioned; internally peer reviewed.