Article Text

Download PDFPDF
Randomised controlled trial
In patients with persistent atrial fibrillation complex ablation techniques were no better than pulmonary vein isolation alone in preventing recurrent atrial fibrillation
  1. Martin Manninger,
  2. Daniel Scherr
  1. Division of Cardiology, Medical University of Graz, Graz, Austria
  1. Correspondence to : Dr. Daniel Scherr, Associate Professor of Medicine, Division of Cardiology, Medical University of Graz, Auenbruggerplatz 15, Graz 8036, Austria; daniel.scherr{at}

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Commentary on: OpenUrlCrossRefPubMed


Pulmonary vein isolation (PVI) is a well-established treatment for patients with paroxysmal atrial fibrillation (AF).1 ,2 Ablation of persistent AF (beyond 7 days) or longstanding persistent AF (>12 months) is less likely to result in permanent sinus rhythm.1 ,2 For this reason, additional ablation methods subsumed as ‘substrate modification’ are often combined with PVI. These methods include ablation of complex fractionated atrial electrograms (CFAEs) and/or creation of linear lesions within the left atrium.


The study reported on a randomised trial …

View Full Text


  • Competing interests None declared.

  • Provenance and peer review Commissioned; internally peer reviewed.