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Systematic review with meta analysis
Percutaneous vertebroplasty does not reduce pain and disability from osteoporotic vertebral compression fracture
  1. Bronek Boszczyk
  1. Nottingham University Hospitals, Nottingham, UK
  1. Correspondence to : Dr Bronek Boszczyk, Nottingham University Hospitals, Nottingham NG7 2UH, UK; bronek.boszczyk{at}

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Commentary on: OpenUrlPubMed


Vertebroplasty is a frequently performed procedure stabilising predominantly osteoporotic vertebral fractures through injection of polymethylmethacrylate (PMMA). Recent placebo-controlled (sham) investigations have assessed the efficacy of vertebroplasty. This Cochrane review provides information about the available randomised controlled trials (RCTs) current to November 2014 and is intended for use in clinical and policy decision-making.


RCTs on adult osteoporotic vertebral fractures published as full articles were considered for inclusion. Comparators were: placebo/sham; supportive care; balloon kyphoplasty or similar procedure; pharmacological treatment; or other form of intervention. Outcome data on pain, disability, quality …

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  • Competing interests None declared.

  • Provenance and peer review Commissioned; internally peer reviewed.