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Three trials showing no difference in clinical outcome between patients with acute ischaemic stroke (AIS) treated by mechanical thrombectomy (MT) and those treated by intravenous thrombolysis (IVT) had the effect of reducing the number of patients with AIS receiving endovascular therapy.1–4 Based on the enthusiasm of recent positive findings from the MR CLEAN,5 ESCAPE6 and EXTEND-IA7 trials, the REVASCAT and SWIFT PRIME trials have been stopped prematurely due to their positive findings and their results were released in April 2015. In both studies, MT was performed with the Solitaire revascularisation device, a self-expanding stent used to retrieve thrombi and restore blood flow, showing faster and higher rate of reperfusion, lower intracranial haemorrhage and better outcomes.8
Jovin and colleagues compared safety and efficacy of MT with medical therapy alone. The trial was conducted at four sites in …
Competing interests None declared.
Provenance and peer review Commissioned; internally peer reviewed.
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