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Systematic review
Intermediate and long-term cognitive effects in older adults secondary to cardiovascular procedures is uncommon but current evidence is insufficient
  1. Lesley Charles
  1. Department of Family Medicine, University of Alberta, Edmonton, Alberta, Canada
  1. Correspondence to : Dr Lesley Charles, Department of Family Medicine, University of Alberta, Room 1259, 10230 111 Ave, Edmonton, Alberta, Canada T5G 0B7; lcharles{at}

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Cardiovascular procedures are common in the older population.1 There is suspicion that these procedures may have a negative outcome on cognition.2 However, further research has indicated that there may have been pre-existing cognitive deficits as cognitive impairment is common in the older population.3 This systematic review examines the evidence of the relationship of coronary and carotid revascularisation, cardiac valve replacement and repair and ablation for atrial fibrillation on intermediate-term and long-term cognitive outcomes in adults 65 years or above, including the effects of procedure related stroke or transient ischaemic attack.


This was a systematic review of randomised controlled trials (RCTs) and prospective cohort studies of adults aged 65 years …

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  • Contributors LC contributed substantially to conception and interpretation of data; drafted the article and revised it critically for important intellectual content; gave final approval of the version to be published.

  • Competing interests None declared.

  • Provenance and peer review Commissioned; internally peer reviewed.