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Dual antiplatelet therapy (DAPT) with aspirin plus a P2Y12 receptor antagonist is recommended after drug eluting stent implantation (DES) for at least 12 months by the American College of Cardiology/American Heart Association1 and for 6–12 months by European guidelines. Recent randomised controlled trials (RCT) suggested comparable efficacy of short-term DAPT versus therapy of at least 12 months, raising the question of whether prolonged DAPT offers clinical benefit. However, concerns about DES have arisen regarding the propensity …
Competing interests None declared.
Provenance and peer review Commissioned; internally peer reviewed.