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  • High-sensitivity troponin predicts coronary disease outcomes in type 2 diabetes but yields no benefit in selecting patients for revascularisation

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Therapeutics/Prevention
Randomised controlled trial
High-sensitivity troponin predicts coronary disease outcomes in type 2 diabetes but yields no benefit in selecting patients for revascularisation
  1. Juhani Junttila
  1. Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu, Finland
  1. Correspondence to : Dr Juhani Junttila, Medical Research Center Oulu, University of Oulu and Oulu University Hospital, PO Box 5000, Oulu 90014, Finland; juhani.junttila{at}oulu.fi
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http://dx.doi.org/10.1136/ebmed-2016-110405

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    Commentary on: Everett BM, Brooks MM, Vlachos HE, et al., BARI 2D Study Group. Troponin and cardiac events in stable ischemic heart disease and diabetes. N Engl J Med 2015;373:610–20.OpenUrlCrossRefPubMed

    Context

    High-sensitivity troponin (hs-TnT) assays have been developed for early recognition of patients with acute coronary syndrome (ACS). Additionally, hs-TnT has been shown to be a feasible tool for assessing risk among patients with heart failure. Even though efforts have been made to improve prognosis among patients with coronary artery disease (CAD) with high-risk features, most adverse events occur in patients without these features. Therefore, novel risk markers for ‘intermediate risk’ participants are needed. Recent evidence presents hs-TnT as a promising marker for adverse events among patients with stable CAD.1 ,2 The pathophysiological background for these findings and therapeutic …

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    Footnotes

    • Contributors JJ drafted the manuscript of this commentary.

    • Competing interests None declared.

    • Provenance and peer review Commissioned; internally peer reviewed.

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