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Cohort study
The combination of maternal early pregnancy characteristics and current antenatal blood pressure measurement from 28 weeks’ gestation improves the prediction of women at risk of developing pre-eclampsia
  1. Fergus P McCarthy1,
  2. Louise C Kenny2
  1. 1Division of Women's Health, King's College London, London, UK;
  2. 2The Irish Centre for Fetal and Neonatal Translational Research, University College Cork, Cork, Ireland
  1. Correspondence to : Professor Louise C Kenny, Department of Obstetrics and Gynaecology, 5th Floor, Cork University Maternity Hospital, Wilton, Cork T12 YE02, Ireland; l.kenny{at}

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The accurate prediction of adverse pregnancy outcomes including pre-eclampsia, small for gestational age (SGA) and preterm birth (PTB), remains elusive. These adverse pregnancy outcomes complicate approximately 15% of low-risk pregnancies in nulliparous women and result in significant morbidity and mortality. Early identification of these adverse pregnancy outcomes is one of the major focuses of antenatal care in high resource countries. Accurate prediction of these adverse pregnancy outcomes would allow stratification of high-risk mothers to increased antenatal monitoring ensuring timely detection of disease and the early initiation of potential therapeutic interventions.

This study utilised data from two …

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  • Twitter Follow Louise Kenny at @louiseckenny

  • Contributors FPM interpreted the data. LCK and FPM drafted the work and revised it critically for important intellectual content. Both authors gave final approval of the version published.

  • Competing interests None declared.

  • Provenance and peer review Commissioned; internally peer reviewed.