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Interpreting meta-analysis of continuous outcomes with pre and postvalues
  1. Fares Alahdab,
  2. Feras Zaiem,
  3. Zhen Wang,
  4. M Hassan Murad
  1. Health Care Policy and Research, Mayo Clinic Minnesota, Rochester, Minnesota, USA
  1. Correspondence to : Dr M Hassan Murad
    , Evidence-based Practice Center Mayo Clinic Rochester, MN 55905, USA; murad.mohammad{at}mayo.edu

Extract

Meta-analysis of continuous outcomes that were measured preinterventions and postinterventions are challenging. The pooled estimate, which represents a difference between two changes, can be difficult to clinically interpret and apply to patient care. We present a clinical scenario and a guide for evidence-based medicine learners to facilitate interpretation and application of such estimates.

  • EDUCATION & TRAINING (see Medical Education & Training)
  • EPIDEMIOLOGY
  • GENERAL MEDICINE (see Internal Medicine)
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Extract

Meta-analysis of continuous outcomes that were measured preinterventions and postinterventions are challenging. The pooled estimate, which represents a difference between two changes, can be difficult to clinically interpret and apply to patient care. We present a clinical scenario and a guide for evidence-based medicine learners to facilitate interpretation and application of such estimates.

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Footnotes

  • Contributors FA and MHM conceived the idea of the article. FA drafted the article. All authors contributed to the manuscript and approved its final version.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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