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Interpreting meta-analysis of continuous outcomes with pre and postvalues


Meta-analysis of continuous outcomes that were measured preinterventions and postinterventions are challenging. The pooled estimate, which represents a difference between two changes, can be difficult to clinically interpret and apply to patient care. We present a clinical scenario and a guide for evidence-based medicine learners to facilitate interpretation and application of such estimates.

  • EDUCATION & TRAINING (see Medical Education & Training)
  • GENERAL MEDICINE (see Internal Medicine)

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  • Contributors FA and MHM conceived the idea of the article. FA drafted the article. All authors contributed to the manuscript and approved its final version.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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