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Population-based studies can provide information on the risk of people with autism developing epilepsy. Examination of family members of individuals with epilepsy can also provide a likelihood of a genetic link between autism and epilepsy. Sundelin et al carried out a register-based population study aimed at providing HRs for those with autism (ASD, autism spectrum disorder) developing epilepsy, those with epilepsy having ASD and relatives of people with epilepsy developing ASD.
Cases were identified using the ICD-9 or ICD-10 codes from the Swedish National Patient Register, which includes nationwide inpatient diagnoses from 1987 and, since 2001, hospital-based outpatient care. Siblings, offspring and parents of all participants with epilepsy were identified, with up to five controls matched for …
Competing interests None declared.
Provenance and peer review Commissioned; internally peer reviewed.