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There is uncertainty regarding optimal blood pressure (BP) targets in treating hypertension. Most recent guidelines have recommended a systolic target of <140 mm Hg. The Systolic Blood Pressure Intervention Trial (SPRINT) compared cardiovascular (CV) outcomes in non-diabetic hypertensive patients randomised to standard (systolic blood pressure (SBP) <140 mm Hg) or intensive treatment (<120 mm Hg).1 Composite CV events and total mortality were significantly reduced with intensive treatment. A prespecified analysis evaluated older patients (≥75) and has now been published.
SPRINT compared outcomes with treatment targets of <120 mm Hg and <140 mm Hg in hypertensive patients at medium/high CV risk identified by previous CV events (except stroke), high Framingham risk …
Competing interests None declared.
Provenance and peer review Commissioned; internally peer reviewed.