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  • Nasal continuous positive airway pressure outperforms heated high-flow nasal cannula therapy as primary respiratory therapy in preterm infants

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Therapeutics/Prevention
Randomised controlled trial
Nasal continuous positive airway pressure outperforms heated high-flow nasal cannula therapy as primary respiratory therapy in preterm infants
  1. Sarah J Kotecha1,
  2. Mallinath Chakraborty2,
  3. Sailesh Kotecha1
  1. 1Cardiff University, Cardiff, UK
  2. 2University Hospital of Wales, Cardiff, UK
  1. Correspondence to: Sarah J Kotecha, Department of Child Health, Cardiff University, Heath Park, Cardiff CF14 4XN, UK; kotechasj{at}cardiff.ac.uk

https://doi.org/10.1136/ebmed-2016-110618

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    Commentary on: Roberts CT, Owen LS, Manley BJ, et al. Nasal high-flow therapy for primary respiratory support in preterm infants. N Engl J Med 2016;375:1142–51.OpenUrlPubMed

    Context

    High-flow nasal cannula (HFNC) therapy for preterm newborn infants has quickly gained popularity,1 despite few studies evaluating the underlying mechanisms and lack of high-quality studies evaluating its efficacy.2 Our recent systematic review and meta-analysis,3 and the Cochrane review4 suggested that HFNC therapy was comparable in efficacy to continuous positive airway pressure (CPAP) as a primary mode of support in preterm infants at birth, for respiratory distress syndrome (RDS) in preterm …

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    Footnotes

    • Competing interests None declared.

    • Provenance and peer review Commissioned; internally peer reviewed.