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The primary endpoint in Canakinumab Anti-inflammatory Thrombosis Outcome Study (CANTOS) trial published by Ridker et al 1 was non-fatal myocardial infarction, non-fatal stroke or cardiovascular death. The authors concluded that canakinumab 150 mg reduced primary event rates compared with placebo (3.86 vs 4.11 per 100 person-years) with HR 0.85 (95%CI 0.74 to 0.98; P=0.021). Sample …
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